Reactive arthropathies, FINNGEN

RHEUMA_ARHTROPAT_REACTIVE

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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RHEUMA_ARHTROPAT_REACTIVE

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1987 1129 858
Unadjusted prevalence (%) 0.56 0.57 0.55
Mean age at first event (years) 46.42 44.22 49.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.01 [1.26, 3.21] 3.6e-3 116
15 years 0.01 1.39 [0.85, 2.25] 1.9e-1 53
5 years 0.00 3.09 [1.86, 5.15] 1.4e-5 34
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMA_ARHTROPAT_REACTIVE – Reactive arthropathies, FINNGEN
GWS hits:

Survival analyses between endpoints

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Plot

before Reactive arthropathies, FINNGEN
after Reactive arthropathies, FINNGEN

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies, FINNGEN

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