Reactive arthropathies, FINNGEN

RHEUMA_ARHTROPAT_REACTIVE

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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RHEUMA_ARHTROPAT_REACTIVE

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1987 1129 858
Unadjusted prevalence (%) 0.56 0.57 0.55
Mean age at first event (years) 46.42 44.22 49.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.01 [1.26, 3.21] 3.6e-3 116
15 years 0.01 1.39 [0.85, 2.25] 1.9e-1 53
5 years 0.00 3.09 [1.86, 5.15] 1.4e-5 34
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RHEUMA_ARHTROPAT_REACTIVE – Reactive arthropathies, FINNGEN
GWS hits:

Survival analyses between endpoints

Plot

before Reactive arthropathies, FINNGEN
after Reactive arthropathies, FINNGEN

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies, FINNGEN