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Medicines for HER+ breast cancer

PheWeb

RX_HERPLUS

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC L02B[AG]

11371

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Check pre-conditions, main-only, mode, ICD version None

8557

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Check minimum number of events

Min. number of events 3

8557

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Include endpoints None

8557

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RX_HERPLUS

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 8557 8420 137
Unadjusted prevalence (%) 2.41 4.24 0.09
Mean age at first event (years) 60.17 60.30 52.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.06 [2.97, 5.55] 1.7e-18 765
15 years 0.02 2.60 [1.97, 3.44] 2.1e-11 371
5 years 0.01 6.03 [4.73, 7.71] 4.9e-47 310
1 year 0.00 3.27 [2.16, 4.94] 1.9e-8 31

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_HERPLUS – Medicines for HER+ breast cancer
GWS hits:

Survival analyses between endpoints

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Plot

before Medicines for HER+ breast cancer
after Medicines for HER+ breast cancer

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Medicines for HER+ breast cancer

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