Small fibre neuropathy

SFN

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G60.8, G62.8, G63.3*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G60.8, G62.8, G63.3*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

514

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

514

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Check minimum number of events None

514

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Include endpoints None

514

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SFN

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 514 212 302
Unadjusted prevalence (%) 0.14 0.11 0.19
Mean age at first event (years) 62.02 58.32 64.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 5.86 [3.47, 9.90] 3.9e-11 66
15 years 0.01 2.12 [1.16, 3.88] 1.4e-2 22
5 years 0.01 4.46 [2.46, 8.08] 8.6e-7 26
1 year 0.00 11.23 [5.62, 22.42] 7.2e-12 15

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: SFN – Small fibre neuropathy
GWS hits:

Survival analyses between endpoints

Plot

before Small fibre neuropathy
after Small fibre neuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Small fibre neuropathy