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Asthma and allergy

DOID EFO MESH SNOMED PheWeb

ASTHMA_ALLERG

allergic rhinitis: Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

ALLERG_ASTHMA

8856

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

4256

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ASTHMA_ALLERG

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 4256 3034 1222
Unadjusted prevalence (%) 1.20 1.53 0.78
Mean age at first event (years) 27.11 27.96 25.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.30 [0.82, 2.08] 2.7e-1 77
15 years 0.01 1.28 [0.80, 2.07] 3.0e-1 37
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_ALLERG – Asthma and allergy
GWS hits: 9

Survival analyses between endpoints

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Plot

before Asthma and allergy
after Asthma and allergy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Asthma and allergy

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