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Chronic lower respiratory diseases

DOID EFO MESH SNOMED PheWeb

J10_LOWCHRON

lung disease: A disease involving the lung.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J40-J47
Cause of death: ICD-10 J40-J47

47286

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

47286

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Check minimum number of events None

47286

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Include endpoints

60786

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J10_LOWCHRON

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 60786 32357 28429
Unadjusted prevalence (%) 17.09 16.31 18.06
Mean age at first event (years) 47.07 42.71 52.03

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.73 [2.48, 3.01] 4.6e-89 10350
15 years 0.01 1.76 [1.62, 1.92] 2.5e-38 4051
5 years 0.00 3.59 [3.33, 3.87] <1e-100 2864
1 year 0.00 11.09 [9.99, 12.31] <1e-100 1808

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_LOWCHRON – Chronic lower respiratory diseases
GWS hits: 54

Survival analyses between endpoints

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Plot

before Chronic lower respiratory diseases
after Chronic lower respiratory diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chronic lower respiratory diseases

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