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Alcohol use disorder, ICD-based

PheWeb

AUD

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F10.1, F10.2
Hospital discharge: ICD-9 303
Hospital discharge: ICD-8 303
Cause of death: ICD-10 F10.1, F10.2
Cause of death: ICD-9 303
Cause of death: ICD-8 303

14711

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

14711

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Check minimum number of events None

14711

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Include endpoints None

14711

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AUD

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 14711 4601 10110
Unadjusted prevalence (%) 4.13 2.32 6.42
Mean age at first event (years) 44.86 40.98 46.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.13 [3.46, 4.92] 2.3e-56 2873
15 years 0.02 2.73 [2.38, 3.14] 9.9e-46 1215
5 years 0.01 4.66 [4.14, 5.25] <1e-100 676
1 year 0.00 14.36 [12.40, 16.62] <1e-100 416

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AUD – Alcohol use disorder, ICD-based
GWS hits: 5

Survival analyses between endpoints

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Plot

before Alcohol use disorder, ICD-based
after Alcohol use disorder, ICD-based

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alcohol use disorder, ICD-based

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