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Alcohol dependence

DOID EFO MESH SNOMED PheWeb

F5_ALCOHOL_DEPENDENCE

alcohol dependence: Physical and psychological dependence on alcohol.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F10.2
Hospital discharge: ICD-9 303
Hospital discharge: ICD-8 303
Cause of death: ICD-10 F10.2
Cause of death: ICD-9 303
Cause of death: ICD-8 303

9337

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

9337

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Check minimum number of events None

9337

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Include endpoints None

9337

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F5_ALCOHOL_DEPENDENCE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 F10

Summary Statistics

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Key figures

All Female Male
Number of individuals 9337 2544 6793
Unadjusted prevalence (%) 2.62 1.28 4.32
Mean age at first event (years) 43.45 41.14 44.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.40 [3.70, 5.23] 7.5e-63 2116
15 years 0.02 2.82 [2.47, 3.23] 1.8e-51 880
5 years 0.00 4.46 [3.93, 5.06] <1e-100 439
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_ALCOHOL_DEPENDENCE – Alcohol dependence
GWS hits: 2

Survival analyses between endpoints

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Plot

before Alcohol dependence
after Alcohol dependence

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alcohol dependence

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