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Biguanides

PheWeb

BIGUANIDES

No definition available.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC A10BA

49169

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Check pre-conditions, main-only, mode, ICD version None

44208

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Check minimum number of events

Min. number of events 3

44208

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Include endpoints None

44208

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BIGUANIDES

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 44208 19524 24684
Unadjusted prevalence (%) 12.43 9.84 15.68
Mean age at first event (years) 59.40 57.99 60.52

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.24 [2.02, 2.48] 2.9e-52 6799
15 years 0.01 1.63 [1.48, 1.79] 1.8e-24 3861
5 years 0.00 2.09 [1.92, 2.28] 4.2e-63 1586
1 year 0.00 1.66 [1.41, 1.95] 5.6e-10 226

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: BIGUANIDES – Biguanides
GWS hits:

Survival analyses between endpoints

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Plot

before Biguanides
after Biguanides

loading spinner Loading survival analyses plot