Diabetes mellitus

E4_DIABETES

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

61295

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E4_DIABETES

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Diabetes mellitus based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 61295 27247 34048
Unadjusted prevalence (%) 17.23 13.73 21.63
Mean age at first event (years) 54.72 52.62 56.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.52 [2.30, 2.76] 5.0e-88 10508
15 years 0.01 1.78 [1.65, 1.93] 1.1e-45 5224
5 years 0.00 2.56 [2.38, 2.76] <1e-100 2445
1 year 0.00 4.81 [4.30, 5.38] <1e-100 878

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DIABETES – Diabetes mellitus
GWS hits:

Survival analyses between endpoints

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Plot

before Diabetes mellitus
after Diabetes mellitus

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Drugs most likely to be purchased after Diabetes mellitus

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