Malignant neoplasm of eye, brain and central nervous system

DOID EFO MESH PheWeb

C3_EYE_BRAIN_NEURO

brain neoplasm: A neoplasm (disease) that involves the brain.

Endpoint definition

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FinnGen phenotype data

356077 individuals

Apply sex-specific rule None

356077

Check conditions None

356077

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

C3_EYE_ADNEXA

C3_MENINGES

C3_BRAIN

C3_SPINAL_CORD_CRANIAL_AND_OTHER_CNS

2401

C3_EYE_BRAIN_NEURO

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF4

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Similar endpoints

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List of similar endpoints to Malignant neoplasm of eye, brain and central nervous system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2401	1400	1001
Unadjusted prevalence (%)	0.67	0.71	0.64
Mean age at first event (years)	54.06	52.90	55.68

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.09	5.74 [4.16, 7.92]	1.6e-26	607
15 years	0.01	1.67 [1.18, 2.35]	3.4e-3	128
5 years	0.01	6.86 [5.20, 9.06]	5.9e-42	165
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_EYE_BRAIN_NEURO – Malignant neoplasm of eye, brain and central nervous system
GWS hits:

Survival analyses between endpoints

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Plot

before Malignant neoplasm of eye, brain and central nervous system
after Malignant neoplasm of eye, brain and central nervous system

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Table

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Drugs most likely to be purchased after Malignant neoplasm of eye, brain and central nervous system

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≡ Risteys

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