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Malignant neoplasm of brain

DOID EFO MESH PheWeb

C3_BRAIN

brain neoplasm: A neoplasm (disease) that involves the brain.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Cause of death: ICD-10 C71
Cause of death: ICD-9 191
Cause of death: ICD-8 191
Cancer registry: Topography ICD-O-3 C71

814

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

814

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Check minimum number of events None

814

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Include endpoints None

814

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C3_BRAIN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4

Summary Statistics

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Key figures

All Female Male
Number of individuals 814 367 447
Unadjusted prevalence (%) 0.23 0.18 0.28
Mean age at first event (years) 50.15 46.53 53.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.18 12.13 [2.70, 54.48] 1.1e-3 343
15 years 0.02 2.58 [0.70, 9.54] 1.5e-1 36
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_BRAIN – Malignant neoplasm of brain
GWS hits:

Survival analyses between endpoints

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Plot

before Malignant neoplasm of brain
after Malignant neoplasm of brain

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Drugs most likely to be purchased after Malignant neoplasm of brain

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