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Other malignant neoplasms of skin (=non-melanoma skin cancer)

DOID EFO MESH SNOMED PheWeb

C3_OTHER_SKIN

skin neoplasm: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not C3_MELANOMA_SKIN

353316

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Filter registries

Cause of death: ICD-10 C44
Cause of death: ICD-9 173
Cause of death: ICD-8 173
Cancer registry: Topography ICD-O-3 C44

15341

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions C.O.D: 10, 8, 9

15341

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Check minimum number of events None

15341

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Include endpoints None

15341

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C3_OTHER_SKIN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF6v3

Summary Statistics

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Key figures

All Female Male
Number of individuals 15341 7045 8296
Unadjusted prevalence (%) 4.31 3.55 5.27
Mean age at first event (years) 65.59 63.83 67.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.37 [1.17, 1.60] 9.7e-5 2945
15 years 0.01 0.88 [0.77, 1.00] 5.4e-2 1366
5 years 0.00 1.69 [1.50, 1.89] 3.0e-19 904
1 year 0.00 2.35 [1.99, 2.78] 8.3e-24 238

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: C3_OTHER_SKIN – Other malignant neoplasms of skin (=non-melanoma skin cancer)
GWS hits:

Survival analyses between endpoints

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Plot

before Other malignant neoplasms of skin (=non-melanoma skin cancer)
after Other malignant neoplasms of skin (=non-melanoma skin cancer)

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Drugs most likely to be purchased after Other malignant neoplasms of skin (=non-melanoma skin cancer)

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