Malignant neoplasm of skin


skin neoplasm: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries None


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Check pre-conditions, main-only, mode, ICD version None


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Check minimum number of events None


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Include endpoints


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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 18102 8387 9715
Unadjusted prevalence (%) 5.09 4.23 6.17
Mean age at first event (years) 64.75 62.63 66.59


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.54 [1.33, 1.78] 9.0e-9 3382
15 years 0.01 0.92 [0.81, 1.04] 1.9e-1 1487
5 years 0.00 1.92 [1.73, 2.14] 2.4e-34 1076
1 year 0.00 3.09 [2.66, 3.59] 1.9e-49 327

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: C3_SKIN – Malignant neoplasm of skin
GWS hits:

Survival analyses between endpoints


before Malignant neoplasm of skin
after Malignant neoplasm of skin

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Drugs most likely to be purchased after Malignant neoplasm of skin