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Biliary chirrosis, NAS

DOID EFO MESH SNOMED PheWeb

CHIRBIL_NAS

primary biliary cirrhosis: Primary biliary cholangitis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K74.5
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K74.5
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

71

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

71

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Check minimum number of events None

71

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Include endpoints None

71

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CHIRBIL_NAS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K74
Name in latin Cirrhosis biliaris non specificata

Summary Statistics

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Key figures

All Female Male
Number of individuals 71 47 24
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 61.75 60.42 64.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHIRBIL_NAS – Biliary chirrosis, NAS
GWS hits:

Survival analyses between endpoints

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Plot

before Biliary chirrosis, NAS
after Biliary chirrosis, NAS

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Biliary chirrosis, NAS

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