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Diseases of liver

DOID EFO MESH SNOMED PheWeb

K11_LIVER

liver disease: A disease involving the liver.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 K70-K77, K77.0*B96.8
Cause of death: ICD-10 K70-K77, K77.0*B96.8

8995

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8995

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Check minimum number of events None

8995

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Include endpoints

9859

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K11_LIVER

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 9859 4793 5066
Unadjusted prevalence (%) 2.77 2.42 3.22
Mean age at first event (years) 53.60 52.06 55.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.05 [3.78, 6.73] 3.9e-28 2038
15 years 0.01 2.08 [1.67, 2.60] 9.6e-11 518
5 years 0.01 5.71 [4.83, 6.75] 3.4e-93 479
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_LIVER – Diseases of liver
GWS hits: 8

Survival analyses between endpoints

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Plot

before Diseases of liver
after Diseases of liver

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of liver

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