Chirrosis of liver, NAS

CHIRHEP_NAS

non-alcoholic fatty liver disease: A term referring to fatty replacement of the hepatic parenchyma which is not related to alcohol use.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 K74.6
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K74.6
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1011

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1011

diagram downward connector

Check minimum number of events None

1011

diagram downward connector

Include endpoints None

1011

diagram downward connector
CHIRHEP_NAS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K74
Name in latin Cirrhosis hepatis alia sive non specificata

Summary Statistics

Key figures

All Female Male
Number of individuals 1011 397 614
Unadjusted prevalence (%) 0.28 0.20 0.39
Mean age at first event (years) 63.54 61.05 65.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHIRHEP_NAS – Chirrosis of liver, NAS
GWS hits: 6

Survival analyses between endpoints

Plot

before Chirrosis of liver, NAS
after Chirrosis of liver, NAS

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Chirrosis of liver, NAS