Combinations of oral blood glucose lowering drugs

COMB_ORAL_GLUCLOW

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Medicine purchases: ATC A10BD

7756

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

6814

diagram downward connector
diagram bullet

Check minimum number of events

Min. number of events 3

6814

diagram downward connector

Include endpoints None

6814

diagram downward connector
COMB_ORAL_GLUCLOW

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 6814 2640 4174
Unadjusted prevalence (%) 1.92 1.33 2.65
Mean age at first event (years) 60.98 60.34 61.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.96 [2.29, 3.83] 9.6e-17 560
15 years 0.01 1.92 [1.49, 2.48] 5.4e-7 347
5 years 0.00 3.06 [2.44, 3.84] 6.2e-22 199
1 year 0.00 1.20 [0.69, 2.09] 5.1e-1 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: COMB_ORAL_GLUCLOW – Combinations of oral blood glucose lowering drugs
GWS hits:

Survival analyses between endpoints

Plot

before Combinations of oral blood glucose lowering drugs
after Combinations of oral blood glucose lowering drugs

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Combinations of oral blood glucose lowering drugs