COPD, hospital admissions

COPD_HOSPITAL

chronic obstructive pulmonary disease: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 J44
Hospital discharge: ICD-9 4912
Hospital discharge: ICD-8 49104
Cause of death: ICD-10 $!$
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

15756

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

15756

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Check minimum number of events None

15756

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Include endpoints None

15756

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COPD_HOSPITAL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J40-J47
Name in latin Alii morbi obstructivi chronici pulmonum

Summary Statistics

Key figures

All Female Male
Number of individuals 15756 4068 11688
Unadjusted prevalence (%) 4.43 2.05 7.43
Mean age at first event (years) 65.91 60.84 67.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: COPD_HOSPITAL – COPD, hospital admissions
GWS hits:

Survival analyses between endpoints

Plot

before COPD, hospital admissions
after COPD, hospital admissions

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Drugs most likely to be purchased after COPD, hospital admissions