ICD-8 DM (Sub-endpoint used for defining DM endpoints)

D1_ICD8

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not PANCREATITIS

350432

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Filter registries

Hospital Discharge: ICD-10 $!$
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 250
Cause of death: ICD-10 $!$
Cause of death: ICD-9 $!$
Cause of death: ICD-8 250

7849

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Check pre-conditions, main-only, mode, ICD version

Pre-conditions EVENT_AGE<20
Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1177

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Check minimum number of events None

1177

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Include endpoints None

1177

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D1_ICD8

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1177 682 495
Unadjusted prevalence (%) 0.33 0.34 0.31
Mean age at first event (years) 11.43 11.45 11.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 7.92 [4.40, 14.27] 5.3e-12 77
15 years 0.05 7.68 [4.09, 14.43] 2.2e-10 32
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: D1_ICD8 – ICD-8 DM (Sub-endpoint used for defining DM endpoints)
GWS hits:

Survival analyses between endpoints

Plot

before ICD-8 DM (Sub-endpoint used for defining DM endpoints)
after ICD-8 DM (Sub-endpoint used for defining DM endpoints)

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Drugs most likely to be purchased after ICD-8 DM (Sub-endpoint used for defining DM endpoints)