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Severe non-proliferative background diabetic retinopathy

DOID EFO MESH SNOMED PheWeb

DM_BCKGRND_RETINA_NONPROLIF

proliferative diabetic retinopathy: Later stage of diabetic retinopathy, characterized by neovascularisation of the retina

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H36.02*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H36.02*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

787

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

787

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Check minimum number of events None

787

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Include endpoints None

787

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DM_BCKGRND_RETINA_NONPROLIF

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 787 320 467
Unadjusted prevalence (%) 0.22 0.16 0.30
Mean age at first event (years) 47.40 44.60 49.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.69 [2.31, 9.53] 1.9e-5 97
15 years 0.02 2.81 [1.54, 5.15] 8.0e-4 45
5 years 0.01 7.50 [4.67, 12.02] 6.4e-17 40
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_BCKGRND_RETINA_NONPROLIF – Severe non-proliferative background diabetic retinopathy
GWS hits:

Survival analyses between endpoints

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Plot

before Severe non-proliferative background diabetic retinopathy
after Severe non-proliferative background diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Severe non-proliferative background diabetic retinopathy

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