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Severe diabetic background retinopathy

DOID EFO MESH SNOMED PheWeb

H7_RETINOPATHYDIAB_BKG_SEVERE

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H36.02*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H36.02*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

787

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

787

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Check minimum number of events None

787

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Include endpoints None

787

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H7_RETINOPATHYDIAB_BKG_SEVERE

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 787 320 467
Unadjusted prevalence (%) 0.22 0.16 0.30
Mean age at first event (years) 47.40 44.60 49.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.87 [1.46, 10.22] 6.3e-3 97
15 years 0.02 2.95 [1.36, 6.39] 6.3e-3 45
5 years 0.01 8.13 [4.68, 14.13] 1.1e-13 40
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINOPATHYDIAB_BKG_SEVERE – Severe diabetic background retinopathy
GWS hits: 2

Survival analyses between endpoints

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Plot

before Severe diabetic background retinopathy
after Severe diabetic background retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Severe diabetic background retinopathy

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