≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Diabetic ketoacidosis

DOID EFO MESH SNOMED PheWeb

DM_KETOACIDOSIS

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 E10.01, E10.1, E11.01, E11.1, E12.1, E13.1, E14.1
Hospital discharge: ICD-9 2500
Hospital discharge: ICD-8 $!$
Hospital discharge: excluded ICD-10 E12.1
Cause of death: ICD-10 E10.01, E10.1, E11.01, E11.1, E12.1, E13.1, E14.1
Cause of death: ICD-9 2500
Cause of death: ICD-8 $!$
Cause of death: excluded ICD-10 E12.1

9221

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

7376

diagram downward connector

Check minimum number of events None

7376

diagram downward connector

Include endpoints None

7376

diagram downward connector
DM_KETOACIDOSIS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 7376 3304 4072
Unadjusted prevalence (%) 2.07 1.67 2.59
Mean age at first event (years) 35.89 32.42 38.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 3.97 [3.46, 4.54] 7.1e-88 1779
15 years 0.02 2.24 [2.02, 2.50] 1.6e-50 771
5 years 0.00 3.02 [2.67, 3.41] 1.1e-70 399
1 year 0.00 6.21 [5.17, 7.47] 3.6e-84 173

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: DM_KETOACIDOSIS – Diabetic ketoacidosis
GWS hits: 28

Survival analyses between endpoints

↥

Plot

before Diabetic ketoacidosis
after Diabetic ketoacidosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic ketoacidosis

↥