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Neovascular glaucoma

DOID EFO MESH SNOMED PheWeb

DM_NEOVASCULAR_GLAUCOMA

neovascular glaucoma: Neovascular glaucoma is the most common type of secondary glaucoma, usually caused by diabetic retinopathy, central retinal vein occlusion and carotid artery obstruction but sometimes by trauma, uvietis or ocular tumors, and characterized by severe eye pain, synechial angle glaucoma, high intraocular pressure and leading to loss of vision.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H40.5
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H40.5
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

1022

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1022

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Check minimum number of events None

1022

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Include endpoints None

1022

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DM_NEOVASCULAR_GLAUCOMA

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma [secundarium] post aliam morbositatem oculi

Summary Statistics

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Key figures

All Female Male
Number of individuals 1022 467 555
Unadjusted prevalence (%) 0.29 0.24 0.35
Mean age at first event (years) 60.24 56.80 63.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.78 [2.28, 6.29] 2.8e-7 222
15 years 0.01 1.77 [1.08, 2.91] 2.4e-2 91
5 years 0.01 3.90 [2.69, 5.66] 8.4e-13 91
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_NEOVASCULAR_GLAUCOMA – Neovascular glaucoma
GWS hits: 2

Survival analyses between endpoints

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Plot

before Neovascular glaucoma
after Neovascular glaucoma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Neovascular glaucoma

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