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Glaucoma secondary to other eye disorders

DOID EFO MESH SNOMED PheWeb

H7_GLAUCSECDISEASE

open-angle glaucoma: Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H40.5
Hospital discharge: ICD-9 3655|3656A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H40.5
Cause of death: ICD-9 3655|3656A
Cause of death: ICD-8 $!$

1028

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1028

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Check minimum number of events None

1028

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Include endpoints None

1028

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H7_GLAUCSECDISEASE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma [secundarium] post aliam morbositatem oculi

Summary Statistics

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Key figures

All Female Male
Number of individuals 1028 469 559
Unadjusted prevalence (%) 0.29 0.24 0.36
Mean age at first event (years) 60.18 56.77 63.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.60 [1.40, 4.84] 2.6e-3 224
15 years 0.01 1.38 [0.86, 2.22] 1.8e-1 93
5 years 0.00 3.21 [2.10, 4.90] 7.0e-8 91
1 year 0.00 4.31 [2.60, 7.13] 1.4e-8 26

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCSECDISEASE – Glaucoma secondary to other eye disorders
GWS hits:

Survival analyses between endpoints

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Plot

before Glaucoma secondary to other eye disorders
after Glaucoma secondary to other eye disorders

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Drugs most likely to be purchased after Glaucoma secondary to other eye disorders

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