≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Proliferative diabetic retinopathy

DOID EFO MESH SNOMED PheWeb

DM_RETINA_PROLIF

proliferative diabetic retinopathy: Later stage of diabetic retinopathy, characterized by neovascularisation of the retina

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 H36.03*
Hospital discharge: ICD-9 3620B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H36.03*
Cause of death: ICD-9 3620B
Cause of death: ICD-8 $!$
Operations: NOMESCO codes ^CKC10|^CKC15|^CKC12|^CKC50

8076

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

8076

diagram downward connector

Check minimum number of events None

8076

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

8646

diagram downward connector
DM_RETINA_PROLIF

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

↥

List of similar endpoints to Proliferative diabetic retinopathy based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 8646 4137 4509
Unadjusted prevalence (%) 2.43 2.09 2.87
Mean age at first event (years) 55.61 54.38 56.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.25 [1.66, 3.05] 2.0e-7 1148
15 years 0.01 1.51 [1.16, 1.97] 2.3e-3 586
5 years 0.00 2.46 [1.96, 3.10] 1.4e-14 309
1 year 0.00 3.26 [2.42, 4.38] 7.5e-15 75

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: DM_RETINA_PROLIF – Proliferative diabetic retinopathy
GWS hits: 5

Survival analyses between endpoints

↥

Plot

before Proliferative diabetic retinopathy
after Proliferative diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Proliferative diabetic retinopathy

↥