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Unspecified diabetic retinopathy

DOID EFO MESH SNOMED PheWeb

DM_RETINA_NOS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

DM_EYE_OPER

5860

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Filter registries

Hospital Discharge: ICD-10 H3609|E1.7|E1.3
Hospital discharge: ICD-9 3620A|2504
Hospital discharge: ICD-8 25002
Hospital discharge: excluded ICD-10 E12.3+
Cause of death: ICD-10 H3609|E1.7|E1.3
Cause of death: ICD-9 3620A|2504
Cause of death: ICD-8 25002
Cause of death: excluded ICD-10 E12.3+

3139

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3139

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Check minimum number of events None

3139

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Include endpoints None

3139

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DM_RETINA_NOS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3139 1245 1894
Unadjusted prevalence (%) 0.88 0.63 1.20
Mean age at first event (years) 48.61 46.44 50.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.30 [1.62, 3.28] 3.9e-6 520
15 years 0.01 1.60 [1.16, 2.21] 4.4e-3 255
5 years 0.00 2.22 [1.60, 3.06] 1.4e-6 101
1 year 0.00 4.67 [3.10, 7.05] 2.2e-13 39

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_RETINA_NOS – Unspecified diabetic retinopathy
GWS hits: 4

Survival analyses between endpoints

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Plot

before Unspecified diabetic retinopathy
after Unspecified diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified diabetic retinopathy

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