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Proliferative diabetic retinopathy

DOID EFO MESH SNOMED PheWeb

H7_RETINOPATHYDIAB_PROLIF

proliferative diabetic retinopathy: Later stage of diabetic retinopathy, characterized by neovascularisation of the retina

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 H36.03*
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 H36.03*
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

2277

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2277

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Check minimum number of events None

2277

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Include endpoints None

2277

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H7_RETINOPATHYDIAB_PROLIF

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2277 1007 1270
Unadjusted prevalence (%) 0.64 0.51 0.81
Mean age at first event (years) 46.96 44.67 48.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.79 [2.15, 10.63] 1.2e-4 417
15 years 0.03 3.90 [2.25, 6.77] 1.2e-6 211
5 years 0.01 6.98 [4.88, 9.98] 2.1e-26 125
1 year 0.00 5.62 [3.32, 9.51] 1.2e-10 20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINOPATHYDIAB_PROLIF – Proliferative diabetic retinopathy
GWS hits: 6

Survival analyses between endpoints

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Plot

before Proliferative diabetic retinopathy
after Proliferative diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Proliferative diabetic retinopathy

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