Dipeptidyl peptidase 4 (DPP-4) inhibitors

DPP4INH

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Medicine purchases: ATC A10BG

3779

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Check pre-conditions, main-only, mode, ICD version None

2926

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Check minimum number of events

Min. number of events 3

2926

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Include endpoints None

2926

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DPP4INH

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2926 1195 1731
Unadjusted prevalence (%) 0.82 0.60 1.10
Mean age at first event (years) 59.84 58.81 60.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.61 [1.91, 3.57] 2.0e-9 438
15 years 0.02 2.18 [1.61, 2.96] 5.9e-7 331
5 years 0.00 2.08 [1.56, 2.78] 6.8e-7 89
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: DPP4INH – Dipeptidyl peptidase 4 (DPP-4) inhibitors
GWS hits:

Survival analyses between endpoints

Plot

before Dipeptidyl peptidase 4 (DPP-4) inhibitors
after Dipeptidyl peptidase 4 (DPP-4) inhibitors

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Drugs most likely to be purchased after Dipeptidyl peptidase 4 (DPP-4) inhibitors