Type 1 diabetes with other specified/multiple/unspecified complications

E4_DM1NASCOMP

No definition available.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E10.6, E10.6+M14.2, E10.6+M14.6, E10.7, E10.8
Hospital discharge: ICD-9 2507B|2508B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E10.6, E10.6+M14.2, E10.6+M14.6, E10.7, E10.8
Cause of death: ICD-9 2507B|2508B
Cause of death: ICD-8 $!$
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 E10

197133

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5656

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Check minimum number of events None

5656

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Include endpoints None

5656

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E4_DM1NASCOMP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 5656 2696 2960
Unadjusted prevalence (%) 1.59 1.36 1.88
Mean age at first event (years) 37.08 34.84 39.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.15 [3.50, 7.57] 8.0e-17 666
15 years 0.02 3.70 [2.78, 4.93] 4.9e-19 317
5 years 0.01 5.83 [4.43, 7.68] 2.1e-36 156
1 year 0.00 12.69 [9.20, 17.51] 4.9e-54 66

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_DM1NASCOMP – Type 1 diabetes with other specified/multiple/unspecified complications
GWS hits: 28

Survival analyses between endpoints

Plot

before Type 1 diabetes with other specified/multiple/unspecified complications
after Type 1 diabetes with other specified/multiple/unspecified complications

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Drugs most likely to be purchased after Type 1 diabetes with other specified/multiple/unspecified complications