≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Nontoxic multinodular goitre

DOID EFO MESH SNOMED PheWeb

E4_GOITREMULTINOD

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 E04.2
Hospital discharge: ICD-9 2411
Hospital discharge: ICD-8 241
Cause of death: ICD-10 E04.2
Cause of death: ICD-9 2411
Cause of death: ICD-8 241

6123

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5684

diagram downward connector

Check minimum number of events None

5684

diagram downward connector

Include endpoints None

5684

diagram downward connector
E4_GOITREMULTINOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E04
Name in latin Struma atoxica multinodularis

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 5684 4824 860
Unadjusted prevalence (%) 1.60 2.43 0.55
Mean age at first event (years) 52.38 51.27 58.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.22 [0.93, 1.60] 1.6e-1 455
15 years 0.01 0.92 [0.72, 1.18] 5.3e-1 204
5 years 0.00 1.43 [1.09, 1.88] 9.7e-3 85
1 year 0.00 1.49 [0.89, 2.49] 1.3e-1 17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_GOITREMULTINOD – Nontoxic multinodular goitre
GWS hits: 39

Survival analyses between endpoints

↥

Plot

before Nontoxic multinodular goitre
after Nontoxic multinodular goitre

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Nontoxic multinodular goitre

↥