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Hyperaldosteronism

DOID EFO MESH SNOMED PheWeb

E4_HYPERALDO

hyperaldosteronism: Overproduction of aldosterone by the adrenal glands, which may lead to hypokalemia and/or hypernatremia. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E26
Hospital discharge: ICD-9 2551
Hospital discharge: ICD-8 25500
Cause of death: ICD-10 E26
Cause of death: ICD-9 2551
Cause of death: ICD-8 25500

662

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

627

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Check minimum number of events None

627

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Include endpoints None

627

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E4_HYPERALDO

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Hyperaldosteronismus

Summary Statistics

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Key figures

All Female Male
Number of individuals 627 348 279
Unadjusted prevalence (%) 0.18 0.18 0.18
Mean age at first event (years) 55.65 53.44 58.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.30 [1.25, 4.24] 7.5e-3 49
15 years 0.01 1.30 [0.65, 2.59] 4.6e-1 25
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYPERALDO – Hyperaldosteronism
GWS hits: 1

Survival analyses between endpoints

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Plot

before Hyperaldosteronism
after Hyperaldosteronism

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hyperaldosteronism

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