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Obesity due to excess calories

DOID EFO MESH SNOMED PheWeb

E4_OBESITYCAL

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E66.00, E66.01
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E66.00, E66.01
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

13250

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

13250

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Check minimum number of events None

13250

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Include endpoints None

13250

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E4_OBESITYCAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 13250 8618 4632
Unadjusted prevalence (%) 3.72 4.34 2.94
Mean age at first event (years) 49.80 47.20 54.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.21 [3.22, 5.51] 9.7e-26 869
15 years 0.02 2.28 [1.71, 3.05] 2.6e-8 377
5 years 0.01 5.06 [3.96, 6.46] 9.4e-39 275
1 year 0.00 13.58 [10.45, 17.65] 7.7e-85 140

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYCAL – Obesity due to excess calories
GWS hits: 12

Survival analyses between endpoints

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Plot

before Obesity due to excess calories
after Obesity due to excess calories

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Drugs most likely to be purchased after Obesity due to excess calories

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