Obesity

E4_OBESITY

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E66
Cause of death: ICD-10 E66

18222

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

18222

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Check minimum number of events None

18222

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E4_OBESITY

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E65-E68
Name in latin Obesitas

Similar endpoints

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List of similar endpoints to Obesity based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 18953 12433 6520
Unadjusted prevalence (%) 5.33 6.27 4.14
Mean age at first event (years) 48.75 46.49 53.06

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.07 [2.45, 3.86] 4.7e-22 1460
15 years 0.01 1.90 [1.57, 2.31] 5.0e-11 612
5 years 0.00 3.82 [3.22, 4.53] 2.5e-53 395
1 year 0.00 13.05 [10.78, 15.79] <1e-100 256

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITY – Obesity
GWS hits: 28

Survival analyses between endpoints

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Plot

before Obesity
after Obesity

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