Obesity, other/unspecified

E4_OBESITYNAS

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E66.8, E66.9
Hospital discharge: ICD-9 2780
Hospital discharge: ICD-8 27799
Cause of death: ICD-10 E66.8, E66.9
Cause of death: ICD-9 2780
Cause of death: ICD-8 27799

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

9881

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E4_OBESITYNAS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 9881 6763 3118
Unadjusted prevalence (%) 2.78 3.41 1.98
Mean age at first event (years) 47.29 45.67 50.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.35 [2.44, 4.59] 8.4e-14 840
15 years 0.01 2.09 [1.64, 2.66] 1.8e-9 337
5 years 0.01 4.33 [3.53, 5.32] 1.2e-44 213
1 year 0.00 17.11 [13.66, 21.43] <1e-100 158

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_OBESITYNAS – Obesity, other/unspecified
GWS hits: 11

Survival analyses between endpoints

Plot

before Obesity, other/unspecified
after Obesity, other/unspecified

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Obesity, other/unspecified