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Extreme obesity with alveolar hypoventilation

DOID EFO MESH SNOMED PheWeb

E4_OBESITYXTRMALV

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E66.2
Hospital discharge: ICD-9 2788A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E66.2
Cause of death: ICD-9 2788A
Cause of death: ICD-8 $!$

928

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

928

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Check minimum number of events None

928

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Include endpoints None

928

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E4_OBESITYXTRMALV

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E66
Name in latin Obesitas extrema cum hypoventilatione alveolari

Summary Statistics

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Key figures

All Female Male
Number of individuals 928 522 406
Unadjusted prevalence (%) 0.26 0.26 0.26
Mean age at first event (years) 58.36 56.85 60.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.19 12.16 [6.93, 21.31] 2.8e-18 160
15 years 0.02 3.03 [1.62, 5.66] 5.1e-4 38
5 years 0.01 10.92 [6.60, 18.07] 1.4e-20 63
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYXTRMALV – Extreme obesity with alveolar hypoventilation
GWS hits: 2

Survival analyses between endpoints

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Plot

before Extreme obesity with alveolar hypoventilation
after Extreme obesity with alveolar hypoventilation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Extreme obesity with alveolar hypoventilation

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