Extreme obesity with alveolar hypoventilation

E4_OBESITYXTRMALV

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 E66.2
Hospital discharge: ICD-9 2788A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E66.2
Cause of death: ICD-9 2788A
Cause of death: ICD-8 $!$

928

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

928

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Check minimum number of events None

928

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Include endpoints None

928

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E4_OBESITYXTRMALV

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E66
Name in latin Obesitas extrema cum hypoventilatione alveolari

Summary Statistics

Key figures

All Female Male
Number of individuals 928 522 406
Unadjusted prevalence (%) 0.26 0.26 0.26
Mean age at first event (years) 58.36 56.85 60.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.19 12.16 [6.93, 21.31] 2.8e-18 160
15 years 0.02 3.03 [1.62, 5.66] 5.1e-4 38
5 years 0.01 10.92 [6.60, 18.07] 1.4e-20 63
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_OBESITYXTRMALV – Extreme obesity with alveolar hypoventilation
GWS hits: 2

Survival analyses between endpoints

Plot

before Extreme obesity with alveolar hypoventilation
after Extreme obesity with alveolar hypoventilation

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Drugs most likely to be purchased after Extreme obesity with alveolar hypoventilation