Ovarian dysfunction


ovarian dysfunction: The inability of the ovaries to function.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule

Sex only females


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 E28
Cause of death: ICD-10 E28


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E20-E35
Name in latin Dysfunctio ovarialis

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 1822 1822 -
Unadjusted prevalence (%) 0.51 0.92 -
Mean age at first event (years) 30.67 30.67 -


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.03 [2.18, 7.45] 8.9e-6 36
15 years 0.02 2.60 [1.25, 5.38] 1.0e-2 12
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_OVARDYS – Ovarian dysfunction
GWS hits: 6

Survival analyses between endpoints


before Ovarian dysfunction
after Ovarian dysfunction

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Drugs most likely to be purchased after Ovarian dysfunction