≡ Risteys
R8

Documentation Changelog GitHub Contact & Feedback

Primary ovarian failure

DOID EFO MESH SNOMED PheWeb

E4_OVARFAIL

primary ovarian insufficiency: Absent or premature cessation of ovarian function due to a pathologic process originating within the ovaries.

Endpoint definition

↥
FinnGen phenotype data

356077 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

198506

diagram downward connector

Check conditions None

198506

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 E28.3
Hospital discharge: ICD-9 2563
Hospital discharge: ICD-8 2561
Cause of death: ICD-10 E28.3
Cause of death: ICD-9 2563
Cause of death: ICD-8 2561
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 E28.3

101503

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

453

diagram downward connector

Check minimum number of events None

453

diagram downward connector

Include endpoints None

453

diagram downward connector
E4_OVARFAIL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E28
Name in latin Insufficientia ovariorum primaria

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 453 453 -
Unadjusted prevalence (%) 0.13 0.23 -
Mean age at first event (years) 35.86 35.86 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 1.91 [0.53, 6.94] 3.2e-1 18
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_OVARFAIL – Primary ovarian failure
GWS hits:

Survival analyses between endpoints

↥

Plot

before Primary ovarian failure
after Primary ovarian failure

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Primary ovarian failure

↥