Schizophrenia, schizotypal and delusional disorders

F5_SCHIZO

schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector

Check conditions None

356077

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 F20
Cause of death: ICD-10 F20

5957

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

5957

diagram downward connector

Check minimum number of events None

5957

diagram downward connector
F5_SCHIZO

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Schizophrenia

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 12929 6661 6268
Unadjusted prevalence (%) 3.63 3.36 3.98
Mean age at first event (years) 34.97 36.00 33.88

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.00 [2.46, 3.66] 1.2e-27 1157
15 years 0.01 1.95 [1.64, 2.31] 2.5e-14 453
5 years 0.00 3.20 [2.71, 3.79] 7.5e-42 226
1 year 0.00 6.31 [4.94, 8.05] 1.5e-49 87

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_SCHIZO – Schizophrenia, schizotypal and delusional disorders
GWS hits:

Survival analyses between endpoints

Plot

before Schizophrenia, schizotypal and delusional disorders
after Schizophrenia, schizotypal and delusional disorders

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Schizophrenia, schizotypal and delusional disorders