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Schizoaffective disorder

DOID EFO MESH PheWeb

F5_SCHIZOAFF

schizoaffective disorder: A disorder in which the individual suffers from both symptoms that qualify as schizophrenia and symptoms that qualify as a mood disorder (e.g., depression or bipolar disorder) for a substantial portion (but not all) of the active period of the illness; for the remainder of the active period of the illness, the individual suffers from delusions or hallucinations in the absence of prominent mood symptoms.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F25
Hospital discharge: ICD-9 2957
Hospital discharge: ICD-8 2957
Cause of death: ICD-10 F25
Cause of death: ICD-9 2957
Cause of death: ICD-8 2957

2730

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2730

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Check minimum number of events None

2730

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Include endpoints None

2730

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F5_SCHIZOAFF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Perturbationes schizoaffectivae

Summary Statistics

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Key figures

All Female Male
Number of individuals 2730 1603 1127
Unadjusted prevalence (%) 0.77 0.81 0.72
Mean age at first event (years) 37.12 37.33 36.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.74 [2.50, 5.60] 1.3e-10 176
15 years 0.02 2.58 [1.76, 3.78] 1.2e-6 71
5 years 0.00 3.60 [2.21, 5.88] 3.0e-7 28
1 year 0.00 9.71 [5.24, 18.01] 5.5e-13 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_SCHIZOAFF – Schizoaffective disorder
GWS hits:

Survival analyses between endpoints

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Plot

before Schizoaffective disorder
after Schizoaffective disorder

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Drugs most likely to be purchased after Schizoaffective disorder

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