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Vascular dementia

DOID EFO MESH SNOMED PheWeb

F5_VASCDEM

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 F01
Hospital discharge: ICD-9 4378
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F01
Cause of death: ICD-9 4378
Cause of death: ICD-8 $!$

2111

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2111

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Check minimum number of events None

2111

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Include endpoints None

2111

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F5_VASCDEM

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F00-F03
Name in latin Dementia vascularis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2111 677 1434
Unadjusted prevalence (%) 0.59 0.34 0.91
Mean age at first event (years) 78.86 80.87 77.91

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.20 12.80 [11.06, 14.80] <1e-100 1357
15 years 0.02 2.35 [2.00, 2.75] 9.7e-26 228
5 years 0.01 7.51 [6.56, 8.59] <1e-100 515
1 year 0.01 28.02 [24.45, 32.11] <1e-100 608

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_VASCDEM – Vascular dementia
GWS hits: 2

Survival analyses between endpoints

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Plot

before Vascular dementia
after Vascular dementia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vascular dementia

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