Vascular dementia


vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 F01
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 F01
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F00-F03
Name in latin Dementia vascularis

Summary Statistics

Key figures

All Female Male
Number of individuals 2064 663 1401
Unadjusted prevalence (%) 0.58 0.33 0.89
Mean age at first event (years) 79.32 81.44 78.31


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 6.98 [3.16, 15.42] 1.5e-6 1340
15 years 0.01 1.56 [0.92, 2.67] 1.0e-1 216
5 years 0.01 6.32 [5.05, 7.92] 5.0e-58 512
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_VASCDEM – Vascular dementia
GWS hits: 2

Survival analyses between endpoints


before Vascular dementia
after Vascular dementia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vascular dementia