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Focal epilepsy, mode (most common among epilepsy diagnosis)

DOID EFO MESH SNOMED PheWeb

FE_MODE

partial epilepsy: A seizure caused by a localized disorder.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G40.3
Hospital discharge: ICD-9 %345[4-5]
Hospital discharge: ICD-8 %3453
Cause of death: ICD-10 G40.3
Cause of death: ICD-9 %345[4-5]
Cause of death: ICD-8 %3453

9390

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Check pre-conditions, main-only, mode, ICD version

Check mode of ICD-10 codes: %3453, %345[4-5], %G403
Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1164

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Check minimum number of events None

1164

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Include endpoints None

1164

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FE_MODE

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 1164 681 483
Unadjusted prevalence (%) 0.33 0.34 0.31
Mean age at first event (years) 28.12 25.69 31.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.21 [2.42, 4.25] 5.5e-16 139
15 years 0.02 2.04 [1.54, 2.70] 6.4e-7 61
5 years 0.00 2.13 [1.40, 3.22] 3.6e-4 23
1 year 0.00 5.14 [2.75, 9.58] 2.7e-7 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FE_MODE – Focal epilepsy, mode (most common among epilepsy diagnosis)
GWS hits:

Survival analyses between endpoints

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Plot

before Focal epilepsy, mode (most common among epilepsy diagnosis)
after Focal epilepsy, mode (most common among epilepsy diagnosis)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Focal epilepsy, mode (most common among epilepsy diagnosis)

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