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Motor neuron disease

DOID EFO MESH SNOMED PheWeb

G6_ALS

motor neuron disease: A disease involving the motor neuron.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G12.2
Hospital discharge: ICD-9 3352A
Hospital discharge: ICD-8 348[0-1]|34821
Cause of death: ICD-10 G12.2
Cause of death: ICD-9 3352A
Cause of death: ICD-8 348[0-1]|34821

473

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

438

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Check minimum number of events None

438

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Include endpoints None

438

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G6_ALS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G12
Name in latin Morbus motoneuronalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 438 161 277
Unadjusted prevalence (%) 0.12 0.08 0.18
Mean age at first event (years) 65.02 64.24 65.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_ALS – Motor neuron disease
GWS hits: 2

Survival analyses between endpoints

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Plot

before Motor neuron disease
after Motor neuron disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Motor neuron disease

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