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Cerebral palsy and other paralytic syndromes

DOID EFO MESH SNOMED PheWeb

G6_CPETAL

cerebral palsy: A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G80-G83
Cause of death: ICD-10 G80-G83

2805

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2805

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Check minimum number of events None

2805

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Include endpoints

3266

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G6_CPETAL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3266 1673 1593
Unadjusted prevalence (%) 0.92 0.84 1.01
Mean age at first event (years) 47.08 43.48 50.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.89 [2.64, 5.73] 5.8e-12 653
15 years 0.01 1.67 [1.12, 2.49] 1.2e-2 224
5 years 0.00 3.60 [2.75, 4.71] 9.1e-21 168
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_CPETAL – Cerebral palsy and other paralytic syndromes
GWS hits:

Survival analyses between endpoints

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Plot

before Cerebral palsy and other paralytic syndromes
after Cerebral palsy and other paralytic syndromes

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Drugs most likely to be purchased after Cerebral palsy and other paralytic syndromes

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