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Diabethic neuropathy

DOID EFO MESH SNOMED PheWeb

G6_DIABETNEUR

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G590|E104|E114|E124|E134|E144
Hospital discharge: ICD-9 2505
Hospital discharge: ICD-8 25005
Cause of death: ICD-10 G590|E104|E114|E124|E134|E144
Cause of death: ICD-9 2505
Cause of death: ICD-8 25005

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

2514

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G6_DIABETNEUR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2514 898 1616
Unadjusted prevalence (%) 0.71 0.45 1.03
Mean age at first event (years) 56.93 54.11 58.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.09 [3.08, 5.43] 2.8e-22 694
15 years 0.01 2.13 [1.61, 2.81] 1.3e-7 298
5 years 0.00 3.76 [2.95, 4.80] 1.3e-26 203
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_DIABETNEUR – Diabethic neuropathy
GWS hits:

Survival analyses between endpoints

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Plot

before Diabethic neuropathy
after Diabethic neuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabethic neuropathy

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