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Diabetic autonomic neuropathy

DOID EFO MESH SNOMED PheWeb

DM_AUTONOMIC

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G99.0*E10.4, G99.0*E11.4
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G99.0*E10.4, G99.0*E11.4
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

97

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DM_AUTONOMIC

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 97 32 65
Unadjusted prevalence (%) 0.03 0.02 0.04
Mean age at first event (years) 54.13 45.54 58.36

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: DM_AUTONOMIC – Diabetic autonomic neuropathy
GWS hits:

Survival analyses between endpoints

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Plot

before Diabetic autonomic neuropathy
after Diabetic autonomic neuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic autonomic neuropathy

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