Bacterial meningitis

G6_MENINGBACT

bacterial meningitis: Inflammation of the membranes surrounding the brain and spinal cord due to a bacterial infection.

Endpoint definition

FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G0[0-1]
Hospital discharge: ICD-9 320
Hospital discharge: ICD-8 320
Cause of death: ICD-10 G0[0-1]
Cause of death: ICD-9 320
Cause of death: ICD-8 320

905

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

905

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Check minimum number of events None

905

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Include endpoints None

905

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G6_MENINGBACT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 905 460 445
Unadjusted prevalence (%) 0.25 0.23 0.28
Mean age at first event (years) 32.00 30.20 33.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.34 [1.21, 4.51] 1.1e-2 91
15 years 0.01 1.38 [0.77, 2.47] 2.9e-1 30
5 years 0.00 1.72 [0.82, 3.57] 1.5e-1 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_MENINGBACT – Bacterial meningitis
GWS hits:

Survival analyses between endpoints

Plot

before Bacterial meningitis
after Bacterial meningitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Bacterial meningitis