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Inflammatory diseases of the central nervous system

DOID EFO MESH SNOMED PheWeb

G6_NEUINFL

encephalomyelitis: Inflammation of the brain and the spinal cord.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 G00-G09
Cause of death: ICD-10 G00-G09

1483

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1483

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Check minimum number of events None

1483

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Include endpoints

2236

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G6_NEUINFL

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2236 1202 1034
Unadjusted prevalence (%) 0.63 0.61 0.66
Mean age at first event (years) 40.84 38.75 43.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.66 [2.19, 6.12] 6.9e-7 287
15 years 0.01 1.47 [0.98, 2.20] 6.3e-2 77
5 years 0.01 3.85 [2.67, 5.54] 4.1e-13 77
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_NEUINFL – Inflammatory diseases of the central nervous system
GWS hits:

Survival analyses between endpoints

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Plot

before Inflammatory diseases of the central nervous system
after Inflammatory diseases of the central nervous system

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Drugs most likely to be purchased after Inflammatory diseases of the central nervous system

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