Generalized epilepsy, strict definition

GE_STRICT

generalised epilepsy: A chronic condition characterised by recurrent generalised seizures.

Endpoint definition

FinnGen phenotype data

356077 individuals

diagram downward connector

Apply sex-specific rule None

356077

diagram downward connector
diagram bullet

Check conditions

not FE

349947

diagram downward connector

Filter registries None

0

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

GE

626

diagram downward connector
GE_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 626 384 242
Unadjusted prevalence (%) 0.18 0.19 0.15
Mean age at first event (years) 30.30 28.79 32.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.09 [1.76, 9.50] 1.0e-3 58
15 years 0.02 2.17 [0.84, 5.63] 1.1e-1 27
5 years 0.01 3.52 [1.48, 8.37] 4.5e-3 14
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GE_STRICT – Generalized epilepsy, strict definition
GWS hits:

Survival analyses between endpoints

Plot

before Generalized epilepsy, strict definition
after Generalized epilepsy, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Generalized epilepsy, strict definition