Generalized epilepsy, strict definition

GE_STRICT

generalised epilepsy: A chronic condition characterised by recurrent generalised seizures.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions

not FE

349947

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

GE

626

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GE_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 626 384 242
Unadjusted prevalence (%) 0.18 0.19 0.15
Mean age at first event (years) 30.30 28.79 32.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.09 [1.76, 9.50] 1.0e-3 58
15 years 0.02 2.17 [0.84, 5.63] 1.1e-1 27
5 years 0.01 3.52 [1.48, 8.37] 4.5e-3 14
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GE_STRICT – Generalized epilepsy, strict definition
GWS hits:

Survival analyses between endpoints

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Plot

before Generalized epilepsy, strict definition
after Generalized epilepsy, strict definition

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Drugs most likely to be purchased after Generalized epilepsy, strict definition

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