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Giant cell arteritis with polymyalgia rheumatica

DOID EFO MESH SNOMED PheWeb

GIANT_CELL_TEMP_ARTERITIS

polymyalgia rheumatica: Polymyalgia rheumatica is a common inflammatory condition that often affects people over the age of 50 years. Characteristic symptoms are shoulder and hip girdle pain and prolonged morning stiffness. Markers of inflammation are often elevated.

Endpoint definition

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FinnGen phenotype data

356077 individuals

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Apply sex-specific rule None

356077

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Check conditions None

356077

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Filter registries

Hospital Discharge: ICD-10 M31.5
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 M31.5
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$

819

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

819

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Check minimum number of events None

819

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Include endpoints None

819

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GIANT_CELL_TEMP_ARTERITIS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Arteritis gigantocellularis cum polymyalgia reumatica

Summary Statistics

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Key figures

All Female Male
Number of individuals 819 497 322
Unadjusted prevalence (%) 0.23 0.25 0.20
Mean age at first event (years) 68.49 67.62 69.82

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.94 [0.90, 4.18] 8.9e-2 134
15 years 0.01 1.04 [0.58, 1.88] 8.8e-1 51
5 years 0.00 2.31 [1.43, 3.73] 5.9e-4 48
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: GIANT_CELL_TEMP_ARTERITIS – Giant cell arteritis with polymyalgia rheumatica
GWS hits:

Survival analyses between endpoints

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Plot

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after Giant cell arteritis with polymyalgia rheumatica

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Drugs most likely to be purchased after Giant cell arteritis with polymyalgia rheumatica

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